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DEA Schedules Hearing on Proposed Ban of Two Psychedelics

Researchers pushed back when the DEA banned two psychedelic substances in 2022, and now the agency has scheduled an administrative hearing to get additional feedback.

Mistaken Autopsy Report Blames Ketamine for Tragic Hot Air Balloon Crash

After publishing the initial report, the medical examiner updated it to show that medical professionals administered ketamine in an attempt to save the pilot’s life.

Best Movies To Watch On Acid

Tune in and fall into the void

The Teachings of the Chacruna Plant 

Divine union and the bridge to wholeness.

These Smokable Herbal Blends Offer a New Kind of (Legal) High

Move over cannabis. We cover the trendiest botanicals to inhale—but safety first, of course.

The Strength and Teachings of Kambô Medicine

"The spirit of the kambô is strong because it heals many diseases, and that’s why we are preserving this knowledge.” —Panã Kamãnawa

An Herbalist’s Guide to Wild Lettuce (Bitter Lettuce)

From ancient virility herb to modern painkiller, meet the versatile medicinal plant growing right outside

A Forager’s Guide to Wild Lettuce

Nature makes powerful medicines. Here's how to find your own pain-killing herbs.

How To Make Blue Lotus Tincture

An herbalist walks you through how to make your own dreamy potion at home

There’s Now A Way To Stay In DMT Space Longer

“This is where ancient practices and modern technology come together.”

The Night MDMA Saved My Life

When our therapist suggested MDMA, I was taken aback: We were here to get divorced, not dance. But afterwards, nothing would ever be the same again.

This Flower Was Once Called the Scariest in the World—But Why? An Exploration of Sacred Datura.

Meet the plant that produces one of the most powerful and controversial botanical compounds.

Nexus Flipping: What Happens When You Combine MDMA and 2C-B

Harm reduction experts weigh in on what you need to know before you flip.

Tripping on LSD in Isolation Tanks and Talking to Dolphins

Dismissed as a madman and revered as a genius, John C. Lilly is perhaps one of the most far-out researchers to ever experiment with psychedelics.

How Do We Make Sense of DMT Realms?

Many people who try DMT report encounters with otherworldly spirits—but what do they mean? A journalist explores.

There’s a Nationwide Ketamine Shortage—and Patients are Suffering

Opinions vary on the cause and severity of the shortage, but its impact on patients is dangerous.

The Sexy Powers of Damiana—The Psychoactive Hiding in the Supplement Isle

Damiana is a popular smokable herb and supplement. So, is it really an aphrodisiac?

The Quiet Wisdom of the Ayahuasca Plant

Banisteriopsis caapi isn’t psychedelic, but for many, it’s a vital plant medicine with plenty to teach

Nutmeg is an Underestimated Psychoactive. Here’s Why.

The subtle power of nutmeg is long overlooked. These recipes help you tune in.

How the Sonoran Desert Toad Became an Obsession of Mainstream Psychedelia

Inside a decades-long journey to uncover the sacramental origins of the Bufo alvarius toad—and the powerful psychedelic derived from it

WTF is a K-Hole?  

We asked experts about falling into the abyss—and how to get out again

This Legal Psychoactive Plant Enhances Dreaming—But Will We Protect It?

Calea zacatechichi (Mexican Dream Herb) can inspire vivid lucid dreams. But, some worry a changing environment and overharvesting may threaten plant traditions.

Massive Mining Projects Threaten People and Psychedelic Traditions in Amazonia

Yopo is a powerful psychedelic snuff used for healing and shamanic practice in the Amazon's Orinoco basin. Crisis puts people and cultural knowledge at risk.

This Veteran-Founded Church Wants to Sell Psychedelics At Your Local Drug Store

After controversy, the Church of Psilomethoxin has far-out dreams for new business

Forget the Visuals—Psychedelic DiPT Makes You Trip On Sound

The results might not always be music to your ears

MDMA Therapy Moves Closer to Approval

After the latest clinical trial, MDMA therapy for PTSD is “on track” for the FDA to consider in 2024

“Candy Flipping” Might Reduce Challenging Psychedelic Experiences

A study found that people who took MDMA alongside mushrooms or LSD had less negative effects

“Off-Label” Ketamine is More Popular Than Ever—So When Is It Legal?

Ketamine was once confined to an anesthetic. Now, it's an up-and-coming mental health aid.

Kanna Isn’t Psychedelic—So Why Is It So Trippy?

Get out of your head and into your heart

Natural Bath Salts? The Twisted History of the Plant That Produces Cathinone

The natural source of cathinone—better known as bath salts—is an East African plant. Its story is a perplexing one, entangled in the War on Drugs and the War on Terror.

Purple Molly: Hype, Branding, or Fake?

More purple, more pizazz? Probably not

The Quest To Preserve Peruvian Torch—By Planting One Million Sacred Cacti

Sacred cacti like Peruvian Torch are at risk from overharvesting in Peru. A collective wants to replant them

How to Stop an Acid Trip

We'll be blunt: You can't fully "stop" an acid trip. But you may be able to charter a more compassionate course

How Long Does DMT Last?

Some psychedelic journeys take hours. This one takes 15 minutes

1P-LSD: Is This Research Chemical Really a Legal Trip?

This novel psychedelic is viewed as an alternative to regular acid—but it's complicated.

WTF is 3-MMC, Berlin’s Weird New Club Drug?

Introducing the latest trending synthetic

PCP (aka Angel Dust) May Actually Have Therapeutic Potential

Mainstream media has portrayed PCP as a substance that makes people violent and erratic—but that’s not the whole story.

DMT vs. Mushrooms: Are We All Tripping On The Same Thing?

The molecules are similar. The trips are not.

The Ayahuasca Experience: A Pilgrimage to the Spirit

The Ayahuasca experience transcends the chemical; it’s a pilgrimage into the realms of the self and the spirit.

LSD vs. Acid: A Brief History of Acid Slang

Acid. Orange Sunshine. Windowpane. Every generation has its own nickname for LSD. But, no matter what you call it, one thing’s certain—it’s long been a symbol of a peaceful counterculture.

Is Ayahuasca Legal?

Ayahuasca legal status depends on where you are.

Salvia Flowers: Cultivation and Consumption

Salvia flowers are a naturally occurring, legal psychedelic. Here's what to know about these blooms.

What is Salvia?

Salvia is sometimes compared to cannabis or DMT, but it is far different—here's everything you need to know.

MDMA: What is Molly?

Everything you need to know about molly or MDMA, everyone's favorite club drug that's fast becoming an FDA-approved trauma treatment medication.

MDA: Everything You Should Know About the “Sass Drug,” What is MDA, and MDA vs. MDMA

MDA is a cousin of MDMA and the sassafrass tree, but the "sass drug" engenders a different experience in its own right.

What is Ayahuasca? Benefits, Risks, Side Effects

Ayahuasca has increased in popularity around the globe—here's what you should know about this entheogenic plant medicine.

What Is Mescaline? A Guide to this Cactus-Derived Psychedelic

Aldous Huxley popularized mescaline in "The Doors of Perception," but no conversation today about this entheogen is complete without attention paid to indigenous sovereignty and conservation strategies around the mescaline-containing peyote succulent.

Is Salvia Legal?

Salvia Divinorum: legal hallucinogen or banned plant?

GHB Drug: What It’s Like to Trip on GHB

Although GHB is known as the "date rape drug," it is getting big on the party scene.

5-MeO-DMT: The Story Behind the “God Molecule”

This mystical molecule is considered to be a less visual, yet more intense cousin of DMT.

Changa: What is Changa? The Truth About Smokeable Ayahuasca

Changa is fairly new compared to the centuries-old ayahuasca tradition—but both are ways to consume DMT.

How To Make LSD: The Process Explained

While LSD is derived from the ergot fungus, the acid we know and love is synthesized in a lab.

LSA Drug: The Trippy Story Behind the Compound in Morning Glory Plants

The seeds of morning glories and some other plants contain LSA, a cousin of LSD. Here's what to know about the effects of the LSA drug, proper dosage and more.

What is 2C-B? The Complete and Honest Explainer

This novel psychedelic was invented by Sasha Shulgin, the "godfather" of MDMA.

Legal Highs: The Top Legal Psychoactive Plants in the US and Canada

From coffee and kratom to mandrake and morning glories, these plants will cause psychoactive, and even hallucinogenic effects.

The Complete Guide to 4-AcO-DMT: Synthetic Shrooms or in a Class of Its Own?

Call it 4-Acetoxy-DMT, 4-AcO, Psilacetin, O-Acetylpsilocin, or synthetic shrooms, here's everything you should know about this little-known psychedelic research chemical.

What is Kava? A Complete Guide

Side effects, preparation, origins, and everything you should know about the native South Pacific root beverage.

Types of Ketamine—Which One Works Best?

Janssen Pharmaceuticals has patented a filtered version of ketamine called Spravato. Here's the breakdown of all the types of ketamine that exist today, including the generic version that has been around since the Sixties.